HitPredict

Interactor 1: TNPO2 (O14787)
Transportin-2 (Karyopherin beta-2b)
Gene: TNPO2

Interactor 2: NUP98 (P52948)
Nuclear pore complex protein Nup98-Nup96 (EC 3.4.21.-) [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)]
Gene: NUP98

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10875935
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006606 - protein import into nucleus GO:0008139 - nuclear localization sequence binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 897 Hs			1 1817
+	Hs
		858024 TNPO1_HUMAN (2-897): 0: 625: 84.39		NUP98_HUMAN (1-1817): 0: 1506: 100.00
+	Hs
		857978 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		NUP98_HUMAN (1-1817): 0: 1506: 100.00
+	Tt
		101907 G0SGZ5_CHATD (1-897): 2.97e-145: 455: 35.65		NU145_CHATD (4-1716): 0: 617: 19.48
+	Hs
		155550 TNPO2_HUMAN (1-897): 0: 644: 100.00		NU153_HUMAN (1-241): 3.42e-12: 74: 18.78
+	Hs
		834652 TNPO1_HUMAN (2-897): 0: 625: 84.39		NU153_HUMAN (1-241): 3.42e-12: 74: 18.78
+	Xl
		1137359 Q5U4V0_XENLA (2-897): 0: 614: 83.95		NU153_XENLA (9-548): 2.21e-15: 84.7: 18.09
+	Hs
		727300 TNPO1_HUMAN (2-897): 0: 625: 84.39		NU214_HUMAN (162-710): 1.58e-09: 65.4: 16.40
+	Ce
		248165 O62332_CAEEL (1-897): 9.59e-179: 541: 49.72		CO4A1_CAEEL (1-497): 2.71e-28: 127: 12.48
+	Ce
		248185 O62332_CAEEL (1-897): 9.59e-179: 541: 49.72		Q9U3B9_CAEEL (217-384): 1.62e-09: 65: 26.11
+	Ce
		248166 O62332_CAEEL (1-897): 9.59e-179: 541: 49.72		P91457_CAEEL (7-386): 6.87e-09: 63.1: 18.09
+	Sc
		746520 IMB2_YEAST (2-894): 6.74e-101: 337: 30.25		NU145_YEAST (295-1314): 5.45e-42: 171: 16.54
+	Sc
		746534 IMB2_YEAST (2-894): 6.74e-101: 337: 30.25		NU116_YEAST (3-603): 7.9e-21: 102: 16.28
+	Sc
		746533 IMB2_YEAST (2-894): 6.74e-101: 337: 30.25		NU100_YEAST (147-754): 1.94e-18: 94.4: 11.51
+	Sc
		746532 IMB2_YEAST (2-894): 6.74e-101: 337: 30.25		NUP49_YEAST (1-184): 2.29e-13: 76.6: 27.60
+	At
		1321465 IMB1_ARATH (9-851): 4.27e-101: 336: 15.32		NUP1_ARATH (1-432): 9.64e-13: 76: 15.70
+	Sc
		746518 IMB2_YEAST (2-894): 6.74e-101: 337: 30.25		NUP57_YEAST (1-164): 1.9e-10: 67.7: 27.06
+	Hs
		727228 XPO2_HUMAN (3-896): 5.07e-90: 308: 13.52		NU214_HUMAN (162-710): 1.58e-09: 65.4: 16.40
+	Hs
		834599 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		NU153_HUMAN (1-241): 3.42e-12: 74: 18.78
+	Hs
		727254 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		NU214_HUMAN (162-710): 1.58e-09: 65.4: 16.40
+	Hs
		1060869 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		P121A_HUMAN (2-326): 2.46e-09: 64.8: 14.42