HitPredict

Interactor 1: TNPO2 (O14787)
Transportin-2 (Karyopherin beta-2b)
Gene: TNPO2

Interactor 2: KCC2D (Q13557)
Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)
Gene: CAMK2D

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	25416956, 31515488
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	HEAT~Pkinase
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 897 Hs			1 499
+	Hs
		155570 TNPO2_HUMAN (1-897): 0: 644: 100.00		KCC2G_HUMAN (1-478): 0: 646: 75.45
+	Hs
		155569 TNPO2_HUMAN (1-897): 0: 644: 100.00		KCC2B_HUMAN (228-478): 1.5e-64: 223: 50.20
+	Mm
		515222 IMB1_MOUSE (11-871): 1.4e-85: 294: 17.62		KCC2A_MOUSE (1-474): 0: 542: 87.58