Interactor 1: GDF8 (O14793)
Growth/differentiation factor 8 (GDF-8) (Myostatin)
Gene: MSTN
Interactor 2: GDF15 (Q99988)
Growth/differentiation factor 15 (GDF-15) (Macrophage inhibitory cytokine 1) (MIC-1) (NSAID-activated gene 1 protein) (NAG-1) (NSAID-regulated gene 1 protein) (NRG-1) (Placental TGF-beta) (Placental bone morphogenetic protein) (Prostate differentiation factor)
Gene: GDF15
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | TGF_beta~TGF_beta, TGF_beta~TGFb_propeptide |
| Common GO terms | GO:0005125 - cytokine activity GO:0005615 - extracellular space GO:0007179 - transforming growth factor beta receptor signaling pathway GO:0008083 - growth factor activity GO:0042803 - protein homodimerization activity |
| Homologous interactions | 16 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
