Interactor 1: UN13B (O14795)
Protein unc-13 homolog B (Munc13-2) (munc13)
Gene: UNC13B

Interactor 2: RIMS1 (Q86UR5)
Regulating synaptic membrane exocytosis protein 1 (Rab-3-interacting molecule 1) (RIM 1) (Rab-3-interacting protein 2)
Gene: RIMS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.836

The method score is based on:

Property Details
Experiments 11343654, 12163476, 37207277
Identification Methods two hybrid, pull down, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~C2, C2~C2
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0031267 - small GTPase binding
GO:0042734 - presynaptic membrane
GO:0048786 - presynaptic active zone
and 2 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1591
Hs

1 1692
+ Hs
+ Hs
+ Hs
+ Rn
+ Rn
+ Hs
+ Hs
+ Hs
+ Ce
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024