HitPredict

Interactor 1: SH21B (O14796)
SH2 domain-containing protein 1B (EWS/FLI1-activated transcript 2) (EAT-2)
Gene: SH2D1B

Interactor 2: Q53HF2 (Q53HF2)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8)
Gene: Q53HF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.45	0.50	0.477

Property	Details
Experiments	unassigned1126
Identification Methods	two hybrid array, luminescence based mammalian interactome mapping, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 132 Hs			1 493
+	Hs
		176362 SHIP2_HUMAN (5-102): 1.32e-36: 133: 42.86		HSP7C_HUMAN (1-473): 0: 768: 98.31
+	Hs
		411965 FYN_HUMAN (3-125): 5.83e-35: 128: 22.48		HSP7C_HUMAN (1-473): 0: 768: 98.31
+	Hs
		337324 ABL1_HUMAN (5-131): 2.58e-34: 127: 25.78		HSP7C_HUMAN (1-473): 0: 768: 98.31
+	Hs
		503596 CSK_HUMAN (3-131): 2.76e-35: 127: 23.26		HSP7C_HUMAN (1-473): 0: 768: 98.31
+	Hs
		411570 LCK_HUMAN (3-127): 1.87e-34: 126: 25.19		HSP7C_HUMAN (1-473): 0: 768: 98.31
+	Hs
		433227 YES_HUMAN (3-125): 1.4e-34: 126: 23.26		HSP7C_HUMAN (1-473): 0: 768: 98.31
+	Hs
		442767 HCK_HUMAN (3-125): 2.65e-34: 126: 25.58		HSP7C_HUMAN (1-473): 0: 768: 98.31
+	Hs
		503608 ABL2_HUMAN (5-131): 3.02e-34: 126: 25.00		HSP7C_HUMAN (1-473): 0: 768: 98.31
+	Hs
		503340 SRC_HUMAN (3-125): 2.31e-33: 123: 25.58		HSP7C_HUMAN (1-473): 0: 768: 98.31
+	Hs
		176375 SHIP2_HUMAN (5-102): 1.32e-36: 133: 42.86		HSP76_HUMAN (2-473): 0: 757: 81.99
+	Hs
		176393 SHIP2_HUMAN (5-102): 1.32e-36: 133: 42.86		HS71L_HUMAN (2-473): 0: 752: 85.81
+	Hs
		564025 CSK_HUMAN (3-131): 2.76e-35: 127: 23.26		HSP76_HUMAN (2-473): 0: 757: 81.99
+	Hs
		411586 LCK_HUMAN (3-127): 1.87e-34: 126: 25.19		HSP76_HUMAN (2-473): 0: 757: 81.99
+	Hs
		442775 HCK_HUMAN (3-125): 2.65e-34: 126: 25.58		HSP76_HUMAN (2-473): 0: 757: 81.99
+	Hs
		789047 ABL2_HUMAN (5-131): 3.02e-34: 126: 25.00		HSP72_HUMAN (2-473): 0: 745: 89.24
+	Gg
		94427 KSYK_CHICK (3-103): 5.28e-15: 72: 31.73		HSP70_CHICK (3-473): 0: 792: 88.58
+	Hs
		503853 GRB2_HUMAN (4-88): 3.18e-17: 75.9: 32.94		HSP7C_HUMAN (1-473): 0: 768: 98.31
+	Gg
		94419 KSYK_CHICK (3-103): 5.28e-15: 72: 31.73		HSP7C_CHICK (1-473): 0: 765: 96.62
+	Hs
		713938 GRB2_HUMAN (4-88): 3.18e-17: 75.9: 32.94		HS71L_HUMAN (2-473): 0: 752: 85.81
+	Hs
		483751 KSYK_HUMAN (3-128): 5.12e-14: 69.3: 28.35		HS71A_HUMAN (1-473): 0: 757: 87.53