HitPredict

Interactor 1: RPC1 (O14802)
DNA-directed RNA polymerase III subunit RPC1 (RNA polymerase III subunit C1) (EC 2.7.7.6) (DNA-directed RNA polymerase III largest subunit) (DNA-directed RNA polymerase III subunit A) (RNA polymerase III 155 kDa subunit) (RPC155) (RNA polymerase III subunit C160)
Gene: POLR3A

Interactor 2: RPAP3 (Q9H6T3)
RNA polymerase II-associated protein 3
Gene: RPAP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.709

Property	Details
Experiments	24981860, 28561026, 33961781, 17643375, 25036637
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, luminescence based mammalian interactome mapping
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1390 Hs			1 665
+	Hs
		625041 RPB1_HUMAN (2-1382): 0: 1534: 32.10		RPAP3_HUMAN (1-665): 1.27e-121: 378: 100.00
+	Hs
		156056 RPC1_HUMAN (1-1390): 0: 1782: 100.00		Q9BPW0_HUMAN (131-251): 4.1e-14: 77.4: 32.23
+	Dm
		375655 RPB1_DROME (5-1368): 0: 1538: 31.93		Q9V3E9_DROME (1-279): 1.6e-29: 125: 26.88
+	Hs
		624784 RPB1_HUMAN (2-1382): 0: 1534: 32.10		STIP1_HUMAN (100-594): 6.38e-20: 95.9: 14.23
+	Hs
		624935 RPB1_HUMAN (2-1382): 0: 1534: 32.10		CTR9_HUMAN (203-663): 7.24e-09: 61.2: 9.07
+	Sc
		375250 RPB1_YEAST (1-1381): 0: 1438: 31.80		STI1_YEAST (65-413): 5.16e-14: 77.2: 16.12
+	Hs
		317160 RPA1_HUMAN (1147-1366): 4.77e-51: 200: 23.87		RPAP3_HUMAN (1-665): 1.27e-121: 378: 100.00