HitPredict

Interactor 1: RPC1 (O14802)
DNA-directed RNA polymerase III subunit RPC1 (RNA polymerase III subunit C1) (EC 2.7.7.6) (DNA-directed RNA polymerase III largest subunit) (DNA-directed RNA polymerase III subunit A) (RNA polymerase III 155 kDa subunit) (RPC155) (RNA polymerase III subunit C160)
Gene: POLR3A

Interactor 2: RPC8 (Q9Y535)
DNA-directed RNA polymerase III subunit RPC8 (RNA polymerase III subunit C8) (DNA-directed RNA polymerase III subunit H) (RNA polymerase III subunit 22.9 kDa subunit) (RPC22.9)
Gene: POLR3H

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.895

The method score is based on:

Property Details
Experiments 33961781, 35271311, 17643375, 24981860
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rbc25~RNA_pol_Rpb1_1, RNA_pol_Rpb1_1~SHS2_Rpb7-N, RNA_pol_Rpb1_2~SHS2_Rpb7-N
Common GO terms GO:0003677 - DNA binding
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity
GO:0005654 - nucleoplasm
GO:0005666 - RNA polymerase III complex
GO:0005829 - cytosol
and 2 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1390
Hs

1 204
+ Hs
+ Hs
+ Sc
+ Bt
+ Hs
+ Sp
+ Sc
+ At
+ At
+ At
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024