Interactor 1: CPLX1 (O14810)
Complexin-1 (Complexin I) (CPX I) (Synaphin-2)
Gene: CPLX1

Interactor 2: STX1A (Q16623)
Syntaxin-1A (Neuron-specific antigen HPC-1)
Gene: STX1A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 10449403, 11832227, 12200427
Identification Methods affinity chromatography technology, x-ray crystallography, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SNARE~Synaphin, Synaphin~Syntaxin
Common GO terms GO:0000149 - SNARE binding
GO:0005829 - cytosol
GO:0006887 - exocytosis
GO:0016079 - synaptic vesicle exocytosis
GO:0030073 - insulin secretion
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 134
Hs

1 288
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024