HitPredict

Interactor 1: TSN4 (O14817)
Tetraspanin-4 (Tspan-4) (Novel antigen 2) (NAG-2) (Transmembrane 4 superfamily member 7)
Gene: TSPAN4

Interactor 2: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	9360996
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005178 - integrin binding GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 238 Hs			1 798
+	Hs
		403820 CD151_HUMAN (4-231): 3.46e-59: 189: 32.22		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		403847 TSN5_HUMAN (8-230): 1.43e-58: 187: 26.80		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		50293 TSN11_HUMAN (9-232): 1.07e-58: 187: 31.49		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		403813 TSN7_HUMAN (3-231): 3.93e-58: 186: 23.21		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		403744 CD63_HUMAN (2-231): 6.72e-57: 182: 29.61		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		403839 CD81_HUMAN (2-236): 3.9e-55: 178: 25.51		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		326008 TSN15_HUMAN (2-230): 1.83e-49: 165: 22.71		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		403784 CD9_HUMAN (2-234): 3.22e-50: 165: 24.79		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		326265 TSN12_HUMAN (1-226): 5.12e-48: 162: 27.24		ITB1_HUMAN (1-798): 0: 794: 100.00
+	Hs
		396617 CD151_HUMAN (4-231): 3.46e-59: 189: 32.22		ITB2_HUMAN (23-796): 0: 658: 45.50
+	Hs
		574512 CD81_HUMAN (2-236): 3.9e-55: 178: 25.51		ITB5_HUMAN (19-792): 0: 660: 42.64
+	Hs
		556422 CD151_HUMAN (4-231): 3.46e-59: 189: 32.22		ITB4_HUMAN (11-727): 0: 566: 33.65
+	Hs
		905571 TSN5_HUMAN (8-230): 1.43e-58: 187: 26.80		TEN3_HUMAN (520-739): 8e-38: 155: 19.33
+	Hs
		326243 TSN15_HUMAN (2-230): 1.83e-49: 165: 22.71		TEN3_HUMAN (520-739): 8e-38: 155: 19.33
+	Hs
		602289 CD9_HUMAN (2-234): 3.22e-50: 165: 24.79		TEN3_HUMAN (520-739): 8e-38: 155: 19.33
+	Hs
		905569 TSN5_HUMAN (8-230): 1.43e-58: 187: 26.80		TEN2_HUMAN (597-739): 2.8e-16: 85.9: 18.06
+	Hs
		101394 CD81_HUMAN (2-236): 3.9e-55: 178: 25.51		F8VNQ3_HUMAN (597-739): 1.67e-16: 86.7: 18.06
+	Hs
		326236 TSN15_HUMAN (2-230): 1.83e-49: 165: 22.71		TEN2_HUMAN (597-739): 2.8e-16: 85.9: 18.06
+	Hs
		602286 CD9_HUMAN (2-234): 3.22e-50: 165: 24.79		TEN2_HUMAN (597-739): 2.8e-16: 85.9: 18.06