HitPredict

Interactor 1: TSN4 (O14817)
Tetraspanin-4 (Tspan-4) (Novel antigen 2) (NAG-2) (Transmembrane 4 superfamily member 7)
Gene: TSPAN4

Interactor 2: ITA6 (P23229)
Integrin alpha-6 (CD49 antigen-like family member F) (VLA-6) (CD antigen CD49f) [Cleaved into: Integrin alpha-6 heavy chain; Integrin alpha-6 light chain; Processed integrin alpha-6 (Alpha6p)]
Gene: ITGA6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	9360996
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005178 - integrin binding GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 238 Hs			1 1130
+	Hs
		613224 CD151_HUMAN (4-231): 3.46e-59: 189: 32.22		ITA6_HUMAN (1-1130): 0: 1347: 100.00
+	Hs
		50294 TSN11_HUMAN (9-232): 1.07e-58: 187: 31.49		ITA6_HUMAN (1-1130): 0: 1347: 100.00
+	Hs
		613235 TSN5_HUMAN (8-230): 1.43e-58: 187: 26.80		ITA6_HUMAN (1-1130): 0: 1347: 100.00
+	Hs
		613229 CD81_HUMAN (2-236): 3.9e-55: 178: 25.51		ITA6_HUMAN (1-1130): 0: 1347: 100.00
+	Hs
		819448 CD151_HUMAN (4-231): 3.46e-59: 189: 32.22		ITA7_HUMAN (3-1129): 0: 1183: 47.84
+	Hs
		50296 TSN11_HUMAN (9-232): 1.07e-58: 187: 31.49		ITA7_HUMAN (3-1129): 0: 1183: 47.84
+	Hs
		156133 TSN4_HUMAN (1-238): 3.44e-62: 196: 100.00		ITA3_HUMAN (7-1108): 0: 936: 34.72
+	Hs
		639875 CD151_HUMAN (4-231): 3.46e-59: 189: 32.22		ITA3_HUMAN (7-1108): 0: 936: 34.72
+	Hs
		639879 TSN5_HUMAN (8-230): 1.43e-58: 187: 26.80		ITA3_HUMAN (7-1108): 0: 936: 34.72
+	Hs
		639894 TSN14_HUMAN (8-230): 5.26e-56: 181: 26.00		ITA3_HUMAN (7-1108): 0: 936: 34.72
+	Mm
		192879 CD151_MOUSE (2-231): 1.01e-52: 172: 31.95		ITA3_MOUSE (9-1108): 0: 937: 35.02
+	Hs
		419182 CD81_HUMAN (2-236): 3.9e-55: 178: 25.51		ITAV_HUMAN (21-1083): 0: 880: 25.14
+	Hs
		530541 CD81_HUMAN (2-236): 3.9e-55: 178: 25.51		ITA4_HUMAN (2-1096): 0: 865: 23.40
+	Hs
		443058 CD81_HUMAN (2-236): 3.9e-55: 178: 25.51		ITA5_HUMAN (21-1086): 0: 855: 25.09
+	Hs
		443039 CD9_HUMAN (2-234): 3.22e-50: 165: 24.79		ITA5_HUMAN (21-1086): 0: 855: 25.09
+	Hs
		880206 CD81_HUMAN (2-236): 3.9e-55: 178: 25.51		ITA1_HUMAN (161-1090): 0: 646: 21.01
+	Hs
		595498 CD82_HUMAN (1-236): 8.3e-55: 178: 27.48		ITAL_HUMAN (285-1105): 5.27e-177: 552: 19.06
+	Hs
		566869 TSN5_HUMAN (8-230): 1.43e-58: 187: 26.80		ITA2_HUMAN (20-494): 2.1e-34: 145: 15.22
+	Hs
		566893 TSN14_HUMAN (8-230): 5.26e-56: 181: 26.00		ITA2_HUMAN (20-494): 2.1e-34: 145: 15.22
+	Hs
		91491 CD81_HUMAN (2-236): 3.9e-55: 178: 25.51		E7ESP4_HUMAN (20-494): 1.99e-34: 145: 15.22