HitPredict

Interactor 1: TSN4 (O14817)
Tetraspanin-4 (Tspan-4) (Novel antigen 2) (NAG-2) (Transmembrane 4 superfamily member 7)
Gene: TSPAN4

Interactor 2: CD81 (P60033)
CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81)
Gene: CD81

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	9360996
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Tetraspanin~Tetraspanin
Common GO terms	GO:0005178 - integrin binding GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0031982 - vesicle
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 238 Hs			1 236
+	Hs
		279369 TSN9_HUMAN (1-233): 4.07e-67: 208: 56.22		TSN5_HUMAN (7-235): 3.13e-55: 179: 21.67
+	Hs
		819444 CD151_HUMAN (4-231): 3.46e-59: 189: 32.22		CD81_HUMAN (1-236): 6.2e-63: 197: 100.00
+	Hs
		887767 TSN5_HUMAN (8-230): 1.43e-58: 187: 26.80		CD81_HUMAN (1-236): 6.2e-63: 197: 100.00
+	Hs
		279368 TSN9_HUMAN (1-233): 4.07e-67: 208: 56.22		CD9_HUMAN (1-234): 3.88e-53: 172: 43.59
+	Hs
		156131 TSN4_HUMAN (1-238): 3.44e-62: 196: 100.00		CD9_HUMAN (1-234): 3.88e-53: 172: 43.59
+	Hs
		819445 CD151_HUMAN (4-231): 3.46e-59: 189: 32.22		TSN5_HUMAN (7-235): 3.13e-55: 179: 21.67
+	Hs
		602230 CD151_HUMAN (4-231): 3.46e-59: 189: 32.22		CD9_HUMAN (1-234): 3.88e-53: 172: 43.59
+	Hs
		602239 TSN5_HUMAN (8-230): 1.43e-58: 187: 26.80		CD9_HUMAN (1-234): 3.88e-53: 172: 43.59
+	Hs
		819462 CD151_HUMAN (4-231): 3.46e-59: 189: 32.22		TSN14_HUMAN (11-230): 6.42e-52: 170: 21.65
+	Hs
		279367 TSN9_HUMAN (1-233): 4.07e-67: 208: 56.22		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48
+	Hs
		905534 TSN5_HUMAN (8-230): 1.43e-58: 187: 26.80		TSN14_HUMAN (11-230): 6.42e-52: 170: 21.65
+	Hs
		653088 CD151_HUMAN (4-231): 3.46e-59: 189: 32.22		CD82_HUMAN (4-234): 1.57e-49: 164: 23.11
+	Hs
		237719 CD151_HUMAN (4-231): 3.46e-59: 189: 32.22		TSN2_HUMAN (3-234): 1.88e-44: 150: 39.22
+	Hs
		326042 CD151_HUMAN (4-231): 3.46e-59: 189: 32.22		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48
+	Hs
		209300 TSN6_HUMAN (3-232): 3.5e-59: 188: 23.71		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48
+	Hs
		326051 TSN5_HUMAN (8-230): 1.43e-58: 187: 26.80		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48
+	Hs
		819465 CD151_HUMAN (4-231): 3.46e-59: 189: 32.22		TSN18_HUMAN (5-231): 2.35e-33: 122: 27.67
+	Hs
		819464 CD151_HUMAN (4-231): 3.46e-59: 189: 32.22		Q8WUV1_HUMAN (6-215): 1.89e-09: 58.2: 28.15