HitPredict

Interactor 1: PSA7 (O14818)
Proteasome subunit alpha type-7 (Proteasome subunit RC6-1) (Proteasome subunit XAPC7)
Gene: PSMA7

Interactor 2: PSMF1 (Q92530)
Proteasome inhibitor PI31 subunit (hPI31)
Gene: PSMF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.669

Property	Details
Experiments	33961781, 35271311, 21988832
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005839 - proteasome core complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 271
+	Hs
		656281 PSA5_HUMAN (3-232): 1.08e-94: 279: 35.32		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Hs
		893716 PSA6_HUMAN (2-236): 1.66e-93: 276: 32.64		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Hs
		637501 PSA1_HUMAN (3-244): 5.16e-93: 275: 32.11		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Hs
		637723 PSA2_HUMAN (3-232): 1.61e-48: 161: 37.87		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Dm
		611657 PSA71_DROME (3-229): 3.48e-94: 278: 68.72		PSMF1_DROME (3-270): 5e-108: 315: 29.46
+	Hs
		893684 PSA6_HUMAN (2-236): 1.66e-93: 276: 32.64		Q5QPM9_HUMAN (1-183): 1.97e-104: 302: 100.00