HitPredict

Interactor 1: SCAM3 (O14828)
Secretory carrier-associated membrane protein 3 (Secretory carrier membrane protein 3)
Gene: SCAMP3

Interactor 2: NEDD4 (P46934)
E3 ubiquitin-protein ligase NEDD4 (EC 2.3.2.26) (Cell proliferation-inducing gene 53 protein) (HECT-type E3 ubiquitin transferase NEDD4) (Neural precursor cell expressed developmentally down-regulated protein 4) (NEDD-4)
Gene: NEDD4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.625

Property	Details
Experiments	19158374, 35044719
Identification Methods	two hybrid, affinity chromatography technology, unspecified method, phage display
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 347 Hs			1 1319
+	Hs
		156555 SCAM3_HUMAN (1-347): 7.61e-153: 434: 100.00		WWP1_HUMAN (389-800): 7.48e-49: 191: 17.86
+	Hs
		124999 SCAM3_HUMAN (1-347): 7.61e-153: 434: 100.00		WWP2_HUMAN (461-817): 1.56e-41: 167: 17.91
+	Hs
		156547 SCAM3_HUMAN (1-347): 7.61e-153: 434: 100.00		ITCH_HUMAN (468-799): 2.73e-28: 125: 19.42