HitPredict

Interactor 1: FFAR1 (O14842)
Free fatty acid receptor 1 (G-protein coupled receptor 40)
Gene: FFAR1

Interactor 2: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 300 Hs			1 189
+	Hs
		348541 ADA1B_HUMAN (1-295): 1.05e-66: 218: 16.14		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		349150 CCR1_HUMAN (3-280): 8.74e-69: 219: 21.53		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		686630 CCR1_HUMAN (3-280): 8.74e-69: 219: 21.53		RAB14_HUMAN (4-185): 2.1e-73: 221: 29.35
+	Hs
		428999 ADRB2_HUMAN (10-292): 1.55e-67: 217: 15.67		RAB14_HUMAN (4-185): 2.1e-73: 221: 29.35
+	Hs
		156817 FFAR1_HUMAN (1-300): 1.82e-64: 206: 100.00		RAB14_HUMAN (4-185): 2.1e-73: 221: 29.35
+	Hs
		111024 P2RY6_HUMAN (7-281): 2.06e-49: 168: 24.49		I1SRC5_HUMAN (16-189): 1.49e-85: 255: 85.71
+	Hs
		350181 P2RY6_HUMAN (7-281): 2.06e-49: 168: 24.49		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		674840 AGTR1_HUMAN (2-292): 1.09e-58: 193: 19.74		RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88
+	Hs
		63221 CCR1_HUMAN (3-280): 8.74e-69: 219: 21.53		RP1BL_HUMAN (1-165): 6.97e-60: 186: 55.69
+	Hs
		506375 CXCR4_HUMAN (3-280): 4.27e-65: 209: 20.69		RALA_HUMAN (4-169): 7.15e-59: 184: 53.89