Interactor 1: AIM2 (O14862)
Interferon-inducible protein AIM2 (Absent in melanoma 2)
Gene: AIM2

Interactor 2: AIM2 (O14862)
Interferon-inducible protein AIM2 (Absent in melanoma 2)
Gene: AIM2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.881

The method score is based on:

Property Details
Experiments 25665578, 15582594, 19158676, 24630722
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, cross-linking study, electron microscopy
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HIN~HIN, PYRIN~PYRIN
Common GO terms GO:0002218 - activation of innate immune response
GO:0002221 - pattern recognition receptor signaling pathway
GO:0002230 - positive regulation of defense response to virus by host
GO:0003690 - double-stranded DNA binding
GO:0005654 - nucleoplasm
and 29 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 343
Hs

1 343
+ Mm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024