HitPredict

Interactor 1: BCKD (O14874)
Branched-chain alpha-ketoacid dehydrogenase kinase (BCKDH kinase) (BCKDHKIN) (BDK) (EC 2.7.11.1) ([3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial) (EC 2.7.11.4)
Gene: BCKDK

Interactor 2: FKBP5 (Q13451)
Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase)
Gene: FKBP5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 412 Hs			1 457
+	Hs
		1034861 PDK2_HUMAN (40-412): 5.73e-98: 300: 27.37		FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00
+	Hs
		118644 BCKD_HUMAN (1-412): 4.04e-124: 367: 100.00		AIP_HUMAN (144-414): 1.52e-49: 173: 16.72
+	Hs
		157297 BCKD_HUMAN (1-412): 4.04e-124: 367: 100.00		STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62
+	Hs
		118740 PDK4_HUMAN (41-412): 2.79e-91: 283: 25.71		AIP_HUMAN (144-414): 1.52e-49: 173: 16.72
+	Hs
		684739 PDK2_HUMAN (40-412): 5.73e-98: 300: 27.37		STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62
+	Hs
		684740 PDK3_HUMAN (55-412): 5.14e-93: 287: 26.86		STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62
+	At
		1109849 AHK5_ARATH (139-410): 3.66e-63: 220: 15.86		FKB42_ARATH (1-337): 3.13e-28: 116: 18.13