HitPredict

Interactor 1: IFIT3 (O14879)
Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (CIG49) (ISG-60) (Interferon-induced 60 kDa protein) (IFI-60K) (Interferon-induced protein with tetratricopeptide repeats 4) (IFIT-4) (Retinoic acid-induced gene G protein) (P60) (RIG-G)
Gene: IFIT3

Interactor 2: IFIT3 (O14879)
Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (CIG49) (ISG-60) (Interferon-induced 60 kDa protein) (IFI-60K) (Interferon-induced protein with tetratricopeptide repeats 4) (IFIT-4) (Retinoic acid-induced gene G protein) (P60) (RIG-G)
Gene: IFIT3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.815

The method score is based on:

Property Details
Experiments 16189514, 21163940
Identification Methods two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains TPR_12~TPR_12, TPR_12~TPR_7, TPR_12~TPR_8, TPR_7~TPR_7, TPR_7~TPR_8, TPR_8~TPR_8
Common GO terms GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0008285 - negative regulation of cell population proliferation
GO:0009615 - response to virus
and 3 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 490
Hs

1 490
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Last updated: 15 Jul 2024