HitPredict

Interactor 1: KLF11 (O14901)
Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2)
Gene: KLF11

Interactor 2: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.59	0.60	0.596

Property	Details
Experiments	32814053, 17500595
Identification Methods	validated two hybrid, two hybrid array, two hybrid pooling approach, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006915 - apoptotic process GO:0043065 - positive regulation of apoptotic process
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 512 Hs			1 3142
+	Hs
		792071 ZN180_HUMAN (11-512): 3.4e-103: 325: 15.09		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Hs
		791587 ZKSC8_HUMAN (62-480): 9.63e-74: 245: 17.05		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Hs
		791688 ZFP2_HUMAN (110-477): 2.35e-72: 238: 17.95		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Hs
		791955 ZN436_HUMAN (354-477): 6.02e-55: 193: 34.68		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Hs
		791613 ZN829_HUMAN (329-478): 4.81e-53: 187: 24.24		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Hs
		791793 ZN675_HUMAN (68-252): 8.78e-37: 145: 7.98		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Hs
		434999 SP1_HUMAN (387-503): 9.79e-34: 137: 55.56		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Hs
		791495 SP3_HUMAN (387-482): 2.82e-32: 133: 60.42		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Hs
		792129 KLF12_HUMAN (351-477): 1.26e-31: 127: 52.71		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Hs
		791431 KLF3_HUMAN (390-477): 2.89e-28: 117: 65.91		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Hs
		791997 Z286A_HUMAN (397-497): 4.56e-17: 85.9: 21.19		HD_HUMAN (1-3142): 0: 5724: 100.00