Interactor 1: KLF11 (O14901)
Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2)
Gene: KLF11

Interactor 2: KS6A2 (Q15349)
Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)
Gene: RPS6KA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 32814053
Identification Methods two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~zf-C2H2
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0008285 - negative regulation of cell population proliferation
GO:0043065 - positive regulation of apoptotic process
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 512
Hs

1 733
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024