HitPredict

Interactor 1: KLF11 (O14901)
Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2)
Gene: KLF11

Interactor 2: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 512 Hs			1 669
+	Hs
		549220 ZN250_HUMAN (53-349): 2.12e-68: 231: 9.00		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		549242 ZN250_HUMAN (53-349): 2.12e-68: 231: 9.00		LZTS1_HUMAN (26-653): 2.54e-34: 140: 35.06
+	Hs
		149092 ZN431_HUMAN (101-358): 1.33e-71: 240: 6.85		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		563710 ZKSC1_HUMAN (357-489): 1.18e-57: 202: 34.59		DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41
+	Hs
		846771 KLF5_HUMAN (345-476): 3.68e-31: 127: 51.77		SMCA2_HUMAN (18-531): 1.58e-34: 143: 13.60
+	Hs
		435014 SP1_HUMAN (387-503): 9.79e-34: 137: 55.56		SMCA4_HUMAN (18-526): 1.58e-30: 130: 13.06
+	Hs
		846731 KLF3_HUMAN (390-477): 2.89e-28: 117: 65.91		SMCA2_HUMAN (18-531): 1.58e-34: 143: 13.60
+	Hs
		846958 KLF1_HUMAN (390-477): 1.28e-28: 118: 61.36		SMCA4_HUMAN (18-526): 1.58e-30: 130: 13.06
+	Hs
		563759 ZNF26_HUMAN (109-388): 1.59e-17: 87.2: 10.82		MTCL1_HUMAN (56-644): 5.72e-34: 141: 14.24
+	Hs
		434981 SP1_HUMAN (387-503): 9.79e-34: 137: 55.56		MYH11_HUMAN (141-564): 3.93e-11: 68.9: 11.53
+	Hs
		435195 SP1_HUMAN (387-503): 9.79e-34: 137: 55.56		MRCKB_HUMAN (197-560): 2.09e-10: 66.2: 13.44
+	Hs
		435118 SP1_HUMAN (387-503): 9.79e-34: 137: 55.56		FKB15_HUMAN (49-548): 5.14e-10: 65: 9.00
+	Hs
		563800 ZNF3_HUMAN (112-355): 4.45e-09: 60.6: 11.16		LZTS1_HUMAN (26-653): 2.54e-34: 140: 35.06
+	Hs
		435099 SP1_HUMAN (387-503): 9.79e-34: 137: 55.56		PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77
+	Hs
		435121 SP1_HUMAN (387-503): 9.79e-34: 137: 55.56		MRCKA_HUMAN (328-609): 6.79e-09: 61.6: 11.68
+	Hs
		434980 SP1_HUMAN (387-503): 9.79e-34: 137: 55.56		MYH10_HUMAN (321-640): 8.77e-09: 61.2: 18.79
+	Hs
		149023 ZN695_HUMAN (389-501): 5e-29: 122: 22.60		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		563788 ZNF3_HUMAN (112-355): 4.45e-09: 60.6: 11.16		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52