HitPredict

Interactor 1: GIPC1 (O14908)
PDZ domain-containing protein GIPC1 (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (RGS19-interacting protein 1) (Synectin) (Tax interaction protein 2) (TIP-2)
Gene: GIPC1

Interactor 2: RXRG (P48443)
Retinoic acid receptor RXR-gamma (Nuclear receptor subfamily 2 group B member 3) (Retinoid X receptor gamma)
Gene: RXRG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 333 Hs			1 463
+	Hs
		158137 GIPC1_HUMAN (1-333): 0: 510: 100.00		ESR1_HUMAN (1-458): 9.47e-116: 353: 23.81
+	Hs
		158217 GIPC1_HUMAN (1-333): 0: 510: 100.00		ESR2_HUMAN (21-456): 3.61e-100: 311: 26.82
+	Hs
		370077 GIPC2_HUMAN (1-329): 2.12e-159: 449: 61.40		ESR1_HUMAN (1-458): 9.47e-116: 353: 23.81