HitPredict

Interactor 1: GIPC1 (O14908)
PDZ domain-containing protein GIPC1 (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (RGS19-interacting protein 1) (Synectin) (Tax interaction protein 2) (TIP-2)
Gene: GIPC1

Interactor 2: GIPC2 (Q8TF65)
PDZ domain-containing protein GIPC2
Gene: GIPC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	29467281, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PDZ~PDZ
Common GO terms	GO:0005737 - cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 333 Hs			1 315
+	Rn
		1378281 GIPC1_RAT (1-333): 0: 560: 96.40		GIPC1_RAT (1-311): 2.34e-176: 492: 61.40
+	Mm
		1378258 GIPC1_MOUSE (1-333): 0: 534: 96.40		GIPC1_MOUSE (1-311): 2.59e-168: 472: 60.18
+	Hs
		1257215 GIPC2_HUMAN (1-329): 2.12e-159: 449: 61.40		GIPC2_HUMAN (1-315): 2.21e-176: 491: 100.00
+	Hs
		158211 GIPC1_HUMAN (1-333): 0: 510: 100.00		GIPC3_HUMAN (42-312): 3.88e-144: 410: 60.81