HitPredict

Interactor 1: GIPC1 (O14908)
PDZ domain-containing protein GIPC1 (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (RGS19-interacting protein 1) (Synectin) (Tax interaction protein 2) (TIP-2)
Gene: GIPC1

Interactor 2: PKHA2 (Q9HB19)
Pleckstrin homology domain-containing family A member 2 (PH domain-containing family A member 2) (Tandem PH domain-containing protein 2) (TAPP-2)
Gene: PLEKHA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.653

Property	Details
Experiments	29467281, 32296183, unassigned1304
Identification Methods	proximity labelling technology, two hybrid, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 333 Hs			1 425
+	Hs
		1257220 GIPC2_HUMAN (1-329): 2.12e-159: 449: 61.40		PKHA2_HUMAN (1-425): 2.61e-152: 439: 100.00
+	Hs
		1257214 GIPC3_HUMAN (58-331): 2.12e-149: 424: 67.88		PKHA2_HUMAN (1-425): 2.61e-152: 439: 100.00
+	Hs
		158209 GIPC1_HUMAN (1-333): 0: 510: 100.00		DP13B_HUMAN (91-418): 1.55e-39: 152: 13.21
+	Hs
		158196 GIPC1_HUMAN (1-333): 0: 510: 100.00		PKHA7_HUMAN (118-420): 6.77e-39: 151: 16.81