Interactor 1: GIPC1 (O14908)
PDZ domain-containing protein GIPC1 (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (RGS19-interacting protein 1) (Synectin) (Tax interaction protein 2) (TIP-2)
Gene: GIPC1
Interactor 2: ARHGC (Q9NZN5)
Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF)
Gene: ARHGEF12
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.87 | 1.00 | 0.935 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 29467281, 33961781, 32203420, 35271311, unassigned2213 |
| Identification Methods | proximity labelling technology, two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PDZ~PDZ |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007186 - G protein-coupled receptor signaling pathway GO:0016020 - membrane GO:0070062 - extracellular exosome |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
