HitPredict

Interactor 1: LIN7A (O14910)
Protein lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Tax interaction protein 33) (TIP-33) (Vertebrate lin-7 homolog 1) (Veli-1)
Gene: LIN7A

Interactor 2: DLG4 (P78352)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	10341223
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Guanylate_kin~PDZ, PDZ~PDZ
Common GO terms	GO:0005886 - plasma membrane GO:0016323 - basolateral plasma membrane GO:0045202 - synapse GO:0065003 - protein-containing complex assembly GO:0098839 - postsynaptic density membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 233 Hs			1 724
+	Rn
		677810 LIN7B_RAT (18-214): 2.15e-51: 167: 78.17		DLG4_RAT (1-724): 0: 668: 99.86
+	Hs
		942382 LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17		DLG4_HUMAN (1-724): 0: 667: 100.00
+	Hs
		158282 LIN7A_HUMAN (1-233): 1.49e-59: 189: 100.00		MPP2_HUMAN (2-383): 6.03e-22: 102: 14.54
+	Hs
		158279 LIN7A_HUMAN (1-233): 1.49e-59: 189: 100.00		MPP3_HUMAN (1-328): 1.33e-21: 101: 12.46
+	Hs
		158304 LIN7A_HUMAN (1-233): 1.49e-59: 189: 100.00		PALS2_HUMAN (2-203): 5.54e-21: 99.4: 14.42
+	Hs
		158277 LIN7A_HUMAN (1-233): 1.49e-59: 189: 100.00		DLG1_HUMAN (147-465): 1.89e-19: 95.5: 17.93
+	Hs
		158288 LIN7A_HUMAN (1-233): 1.49e-59: 189: 100.00		MPP7_HUMAN (8-289): 1.03e-19: 95.5: 12.50
+	Hs
		158254 LIN7A_HUMAN (1-233): 1.49e-59: 189: 100.00		CSKP_HUMAN (6-200): 2.34e-19: 95.2: 14.29
+	Hs
		158294 LIN7A_HUMAN (1-233): 1.49e-59: 189: 100.00		PALS1_HUMAN (3-238): 7.09e-18: 90.2: 12.30
+	Hs
		1050415 LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17		MPP2_HUMAN (2-383): 6.03e-22: 102: 14.54
+	Hs
		1032760 LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17		MPP3_HUMAN (1-328): 1.33e-21: 101: 12.46
+	Hs
		1334778 LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17		PALS2_HUMAN (2-203): 5.54e-21: 99.4: 14.42
+	Mm
		251089 LIN7B_MOUSE (18-217): 8.75e-52: 168: 77.00		CSKP_MOUSE (6-200): 2.36e-19: 95.2: 14.29
+	Hs
		1021563 LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17		DLG1_HUMAN (147-465): 1.89e-19: 95.5: 17.93
+	Hs
		1132892 LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17		MPP7_HUMAN (8-289): 1.03e-19: 95.5: 12.50
+	Hs
		159269 LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17		CSKP_HUMAN (6-200): 2.34e-19: 95.2: 14.29
+	Mm
		292491 LIN7C_MOUSE (18-211): 1.25e-50: 165: 79.38		DLG1_MOUSE (147-465): 2.02e-19: 95.5: 18.54
+	Mm
		251090 LIN7C_MOUSE (18-211): 1.25e-50: 165: 79.38		CSKP_MOUSE (6-200): 2.36e-19: 95.2: 14.29
+	Hs
		1232501 LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17		PALS1_HUMAN (3-238): 7.09e-18: 90.2: 12.30
+	Mm
		292498 LIN7C_MOUSE (18-211): 1.25e-50: 165: 79.38		PALS1_MOUSE (3-238): 3.05e-18: 91.3: 12.30