HitPredict

Interactor 1: LIN7A (O14910)
Protein lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Tax interaction protein 33) (TIP-33) (Vertebrate lin-7 homolog 1) (Veli-1)
Gene: LIN7A

Interactor 2: APBA1 (Q02410)
Amyloid-beta A4 precursor protein-binding family A member 1 (Adapter protein X11alpha) (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1)
Gene: APBA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PDZ~PDZ, PDZ~PID
Common GO terms	GO:0005886 - plasma membrane GO:0065003 - protein-containing complex assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 233 Hs			1 837
+	Hs
		970739 LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17		APBA1_HUMAN (1-837): 0: 635: 100.00
+	Hs
		970742 LIN7C_HUMAN (18-211): 1.25e-50: 165: 79.38		APBA1_HUMAN (1-837): 0: 635: 100.00
+	Mm
		70738 LIN7C_MOUSE (18-211): 1.25e-50: 165: 79.38		APBA1_MOUSE (1-837): 0: 622: 92.76
+	Ce
		184638 Q9U245_CAEEL (20-225): 1.76e-43: 147: 62.62		LIN10_CAEEL (354-837): 1.55e-80: 281: 49.02
+	Hs
		158271 LIN7A_HUMAN (1-233): 1.49e-59: 189: 100.00		DLG4_HUMAN (358-759): 3.74e-28: 123: 13.43
+	Hs
		158277 LIN7A_HUMAN (1-233): 1.49e-59: 189: 100.00		DLG1_HUMAN (519-758): 2.64e-24: 111: 16.25
+	Hs
		158295 LIN7A_HUMAN (1-233): 1.49e-59: 189: 100.00		INADL_HUMAN (221-822): 2.55e-22: 105: 12.07
+	Rn
		677810 LIN7B_RAT (18-214): 2.15e-51: 167: 78.17		DLG4_RAT (358-759): 3.45e-28: 123: 13.43
+	Hs
		942382 LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17		DLG4_HUMAN (358-759): 3.74e-28: 123: 13.43
+	Hs
		942387 LIN7C_HUMAN (18-211): 1.25e-50: 165: 79.38		DLG4_HUMAN (358-759): 3.74e-28: 123: 13.43
+	Hs
		158256 LIN7A_HUMAN (1-233): 1.49e-59: 189: 100.00		MPDZ_HUMAN (427-770): 3.39e-18: 92.2: 12.87
+	Mm
		292491 LIN7C_MOUSE (18-211): 1.25e-50: 165: 79.38		DLG1_MOUSE (294-758): 3.35e-25: 114: 13.66
+	Hs
		1021563 LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17		DLG1_HUMAN (519-758): 2.64e-24: 111: 16.25
+	Hs
		1021573 LIN7C_HUMAN (18-211): 1.25e-50: 165: 79.38		DLG1_HUMAN (519-758): 2.64e-24: 111: 16.25
+	Hs
		1246435 LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17		INADL_HUMAN (221-822): 2.55e-22: 105: 12.07
+	Hs
		1246444 LIN7C_HUMAN (18-211): 1.25e-50: 165: 79.38		INADL_HUMAN (221-822): 2.55e-22: 105: 12.07
+	Hs
		280072 LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17		MPDZ_HUMAN (427-770): 3.39e-18: 92.2: 12.87
+	Hs
		280082 LIN7C_HUMAN (18-211): 1.25e-50: 165: 79.38		MPDZ_HUMAN (427-770): 3.39e-18: 92.2: 12.87
+	Hs
		1033831 SNTA1_HUMAN (30-233): 1.54e-33: 127: 21.50		SCRIB_HUMAN (642-817): 3.96e-20: 98.4: 18.46
+	Hs
		1033870 SNTB2_HUMAN (100-202): 5.76e-32: 123: 36.19		SCRIB_HUMAN (642-817): 3.96e-20: 98.4: 18.46