HitPredict

Interactor 1: LIN7A (O14910)
Protein lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Tax interaction protein 33) (TIP-33) (Vertebrate lin-7 homolog 1) (Veli-1)
Gene: LIN7A

Interactor 2: AMOT (Q4VCS5)
Angiomotin
Gene: AMOT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	19615732
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 233 Hs			1 1084
+	Hs
		1119073 LIN7C_HUMAN (18-211): 1.25e-50: 165: 79.38		AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00
+	Mm
		292494 LIN7C_MOUSE (18-211): 1.25e-50: 165: 79.38		AMOT_MOUSE (1-1084): 3.42e-87: 307: 75.11
+	Hs
		1021508 DLG1_HUMAN (29-232): 8.11e-25: 104: 19.63		AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00
+	Hs
		280045 MPDZ_HUMAN (54-177): 8.25e-12: 66.4: 20.16		AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00
+	Mm
		1257405 MPDZ_MOUSE (114-218): 2.73e-12: 67.9: 24.53		AMOT_MOUSE (1-1084): 3.42e-87: 307: 75.11
+	Mm
		292496 LIN7C_MOUSE (18-211): 1.25e-50: 165: 79.38		AMOL1_MOUSE (1-912): 1.67e-43: 173: 43.02
+	Mm
		292493 LIN7C_MOUSE (18-211): 1.25e-50: 165: 79.38		AMOL2_MOUSE (1-853): 8.67e-34: 142: 26.49
+	Hs
		1346112 LIN7C_HUMAN (18-211): 1.25e-50: 165: 79.38		AMOL2_HUMAN (296-902): 3.42e-27: 121: 39.81
+	Mm
		1257408 MPDZ_MOUSE (114-218): 2.73e-12: 67.9: 24.53		AMOL1_MOUSE (1-912): 1.67e-43: 173: 43.02
+	Hs
		280051 MPDZ_HUMAN (54-177): 8.25e-12: 66.4: 20.16		AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98
+	Hs
		61867 LNX1_HUMAN (100-223): 3.93e-14: 72.9: 24.80		CC88B_HUMAN (39-1023): 2.68e-32: 138: 11.95
+	Mm
		1225208 MPDZ_MOUSE (114-218): 2.73e-12: 67.9: 24.53		AMOL2_MOUSE (1-853): 8.67e-34: 142: 26.49
+	Mm
		936586 DLG4_MOUSE (5-232): 6.08e-25: 104: 18.33		ROCK2_MOUSE (357-853): 4.34e-19: 95.7: 11.35
+	Hs
		883949 SYJ2B_HUMAN (105-192): 1.33e-31: 114: 37.63		RRBP1_HUMAN (179-773): 3.57e-12: 73: 12.40
+	Mm
		823534 DLG4_MOUSE (5-232): 6.08e-25: 104: 18.33		CTRO_MOUSE (533-855): 2.5e-11: 70.3: 11.15
+	Rn
		92840 DLG4_RAT (5-232): 1.63e-24: 103: 18.33		CTRO_RAT (533-855): 7.07e-11: 69.1: 11.15
+	Mm
		1143486 DLG4_MOUSE (5-232): 6.08e-25: 104: 18.33		RRBP1_MOUSE (149-759): 2.39e-10: 67.3: 9.98
+	Hs
		724926 LNX1_HUMAN (100-223): 3.93e-14: 72.9: 24.80		MYH9_HUMAN (51-655): 1.51e-14: 81.1: 9.31
+	Hs
		1075407 NHRF2_HUMAN (99-233): 6.35e-20: 88.4: 27.01		ITSN1_HUMAN (554-1077): 1.63e-09: 64.6: 9.32
+	Hs
		149084 LNX1_HUMAN (100-223): 3.93e-14: 72.9: 24.80		CTRO_HUMAN (533-815): 3.66e-12: 73.4: 12.37