HitPredict

Interactor 1: PCD17 (O14917)
Protocadherin-17 (Protocadherin-68)
Gene: PCDH17

Interactor 2: HCN1 (O60741)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1)
Gene: HCN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045211 - postsynaptic membrane GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1159 Hs			1 890
+	Hs
		240300 PCDGL_HUMAN (1-991): 0: 920: 31.53		HCN1_HUMAN (1-890): 0: 684: 100.00
+	Hs
		240304 PCDG3_HUMAN (17-991): 0: 859: 30.29		HCN1_HUMAN (1-890): 0: 684: 100.00
+	Hs
		240306 PCDA2_HUMAN (13-894): 0: 857: 33.00		HCN1_HUMAN (1-890): 0: 684: 100.00
+	Hs
		240302 PCDGD_HUMAN (1-991): 0: 853: 31.09		HCN1_HUMAN (1-890): 0: 684: 100.00
+	Hs
		240305 PCDA8_HUMAN (13-894): 0: 850: 33.67		HCN1_HUMAN (1-890): 0: 684: 100.00
+	Hs
		240307 PCDAB_HUMAN (14-894): 0: 846: 33.15		HCN1_HUMAN (1-890): 0: 684: 100.00
+	Hs
		240298 PCDBF_HUMAN (9-822): 0: 832: 34.84		HCN1_HUMAN (1-890): 0: 684: 100.00
+	Hs
		240265 PCDB8_HUMAN (19-822): 0: 830: 34.65		HCN1_HUMAN (1-890): 0: 684: 100.00
+	Hs
		240297 PCDB2_HUMAN (4-835): 0: 826: 32.30		HCN1_HUMAN (1-890): 0: 684: 100.00
+	Hs
		240296 PCDB3_HUMAN (5-835): 0: 821: 32.94		HCN1_HUMAN (1-890): 0: 684: 100.00
+	Hs
		240266 PCDBA_HUMAN (5-819): 0: 811: 34.30		HCN1_HUMAN (1-890): 0: 684: 100.00
+	Hs
		240294 PCDB7_HUMAN (6-823): 0: 808: 34.75		HCN1_HUMAN (1-890): 0: 684: 100.00
+	Hs
		240299 PCDBE_HUMAN (4-825): 0: 808: 32.57		HCN1_HUMAN (1-890): 0: 684: 100.00
+	Hs
		240309 PCDC2_HUMAN (21-716): 3.66e-163: 512: 42.67		HCN1_HUMAN (1-890): 0: 684: 100.00
+	Hs
		240308 PCDA1_HUMAN (2-462): 1.35e-96: 331: 26.70		HCN1_HUMAN (1-890): 0: 684: 100.00
+	Hs
		240268 PCDA4_HUMAN (2-462): 1.02e-95: 329: 27.75		HCN1_HUMAN (1-890): 0: 684: 100.00
+	Hs
		240303 PCDG6_HUMAN (3-464): 8.78e-94: 323: 25.58		HCN1_HUMAN (1-890): 0: 684: 100.00
+	Hs
		240191 PCD18_HUMAN (1-459): 1.09e-85: 304: 21.68		HCN1_HUMAN (1-890): 0: 684: 100.00
+	Hs
		240203 PCDBG_HUMAN (2-343): 4.5e-56: 211: 22.41		HCN1_HUMAN (1-890): 0: 684: 100.00
+	Hs
		240267 PCDGG_HUMAN (480-1115): 8.27e-44: 174: 12.56		HCN1_HUMAN (1-890): 0: 684: 100.00