HitPredict

Interactor 1: IKKB (O14920)
Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK-2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) (Serine/threonine protein kinase IKBKB) (EC 2.7.11.1)
Gene: IKBKB

Interactor 2: TNR16 (P08138)
Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (Low-affinity nerve growth factor receptor p75NGFR) (Low-affinity nerve growth factor receptor p75NGR) (p75 ICD) (CD antigen CD271)
Gene: NGFR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	12034707, 23017601
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 756 Hs			1 427
+	Mm
		291437 IKKB_MOUSE (1-755): 0: 658: 92.05		TNR1A_MOUSE (29-425): 1.22e-78: 252: 17.33
+	Hs
		158391 IKKB_HUMAN (1-756): 0: 662: 100.00		TNR1A_HUMAN (29-417): 1.27e-76: 247: 18.27
+	Hs
		167447 IKKA_HUMAN (1-742): 2.48e-177: 527: 50.47		TNR16_HUMAN (1-427): 1.17e-115: 346: 100.00
+	Mm
		291439 IKKB_MOUSE (1-755): 0: 658: 92.05		TNR5_MOUSE (13-254): 3.01e-46: 162: 23.90
+	Hs
		158399 IKKB_HUMAN (1-756): 0: 662: 100.00		TNR5_HUMAN (13-254): 4.68e-42: 151: 22.14
+	Mm
		291445 IKKB_MOUSE (1-755): 0: 658: 92.05		TNR4_MOUSE (31-247): 1.78e-37: 139: 23.98
+	Hs
		158417 IKKB_HUMAN (1-756): 0: 662: 100.00		TNR3_HUMAN (23-316): 3.68e-33: 131: 14.92
+	Hs
		167467 IKKA_HUMAN (1-742): 2.48e-177: 527: 50.47		TNR1A_HUMAN (29-417): 1.27e-76: 247: 18.27
+	Mm
		626859 IKKA_MOUSE (1-742): 3.39e-172: 514: 50.20		TNR1A_MOUSE (29-425): 1.22e-78: 252: 17.33
+	Hs
		167470 IKKA_HUMAN (1-742): 2.48e-177: 527: 50.47		TNR1B_HUMAN (8-274): 1.53e-45: 165: 18.32
+	Hs
		167474 IKKA_HUMAN (1-742): 2.48e-177: 527: 50.47		TNR5_HUMAN (13-254): 4.68e-42: 151: 22.14
+	Mm
		648957 IKKA_MOUSE (1-742): 3.39e-172: 514: 50.20		TNR5_MOUSE (13-254): 3.01e-46: 162: 23.90
+	Hs
		167489 IKKA_HUMAN (1-742): 2.48e-177: 527: 50.47		TNR3_HUMAN (23-316): 3.68e-33: 131: 14.92
+	Mm
		812912 IKKA_MOUSE (1-742): 3.39e-172: 514: 50.20		TNR4_MOUSE (31-247): 1.78e-37: 139: 23.98
+	Hs
		584404 IKKE_HUMAN (15-725): 1.15e-127: 398: 20.08		TNR1A_HUMAN (29-417): 1.27e-76: 247: 18.27
+	Hs
		632369 M3K5_HUMAN (14-657): 9.04e-137: 439: 20.00		TNR6_HUMAN (26-148): 1.61e-33: 130: 24.81
+	Hs
		584494 TBK1_HUMAN (15-370): 8.86e-97: 317: 26.49		TNR1A_HUMAN (29-417): 1.27e-76: 247: 18.27