Interactor 1: RGS12 (O14924)
Regulator of G-protein signaling 12 (RGS12)
Gene: RGS12

Interactor 2: GNAI1 (P63096)
Guanine nucleotide-binding protein G(i) subunit alpha-1 (Adenylate cyclase-inhibiting G alpha protein)
Gene: GNAI1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.902

The method score is based on:

Property Details
Experiments 26186194, 28514442, 11387333, 33961781
Identification Methods affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains G-alpha~GoLoco, G-alpha~RGS
Common GO terms GO:0003924 - GTPase activity
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1447
Hs

1 354
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024