HitPredict

Interactor 1: UB2L6 (O14933)
Ubiquitin/ISG15-conjugating enzyme E2 L6 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme L6) (Retinoic acid-induced gene B protein) (RIG-B) (UbcH8) (Ubiquitin carrier protein L6) (Ubiquitin-protein ligase L6)
Gene: UBE2L6

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.27	0.60	0.408

Property	Details
Experiments	37219487
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 153 Hs			1 504
+	Hs
		125000 UB2L6_HUMAN (1-153): 2.2e-98: 281: 100.00		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		159084 UB2L6_HUMAN (1-153): 2.2e-98: 281: 100.00		ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17
+	Hs
		159085 UB2L6_HUMAN (1-153): 2.2e-98: 281: 100.00		NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73
+	Hs
		125808 UB2D4_HUMAN (2-149): 5.5e-76: 224: 38.93		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		125262 UB2D1_HUMAN (2-149): 1.04e-75: 223: 38.93		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		125335 UB2D2_HUMAN (2-149): 3.7e-75: 222: 37.58		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		159031 UB2L6_HUMAN (1-153): 2.2e-98: 281: 100.00		NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26
+	Hs
		1294888 UB2D4_HUMAN (2-149): 5.5e-76: 224: 38.93		ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17
+	Hs
		849411 UB2D1_HUMAN (2-149): 1.04e-75: 223: 38.93		ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17
+	Hs
		919827 UB2D2_HUMAN (2-149): 3.7e-75: 222: 37.58		ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17
+	Hs
		849416 UB2D1_HUMAN (2-149): 1.04e-75: 223: 38.93		NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73
+	Hs
		849452 UB2D1_HUMAN (2-149): 1.04e-75: 223: 38.93		SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05
+	Hs
		919834 UB2D2_HUMAN (2-149): 3.7e-75: 222: 37.58		NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73
+	Hs
		849444 UB2D1_HUMAN (2-149): 1.04e-75: 223: 38.93		WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42
+	Hs
		919860 UB2D2_HUMAN (2-149): 3.7e-75: 222: 37.58		WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42
+	Hs
		808052 UB2D1_HUMAN (2-149): 1.04e-75: 223: 38.93		NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26
+	Hs
		808078 UB2D2_HUMAN (2-149): 3.7e-75: 222: 37.58		NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26
+	Hs
		849451 UB2D1_HUMAN (2-149): 1.04e-75: 223: 38.93		SMUF2_HUMAN (99-504): 4.95e-107: 337: 19.19
+	Hs
		849351 UB2D1_HUMAN (2-149): 1.04e-75: 223: 38.93		HECW1_HUMAN (2-222): 1.33e-24: 110: 14.96
+	Hs
		919762 UB2D2_HUMAN (2-149): 3.7e-75: 222: 37.58		HECW1_HUMAN (2-222): 1.33e-24: 110: 14.96