HitPredict

Interactor 1: CSKP (O14936)
Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)
Gene: CASK

Interactor 2: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	30217970
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 926 Hs			1 255
+	Mm
		910260 DLG4_MOUSE (402-922): 5.68e-145: 449: 22.37		1433E_MOUSE (1-255): 4.87e-154: 430: 100.00
+	Hs
		909730 MARK2_HUMAN (4-680): 5.16e-140: 438: 18.64		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Dm
		677686 DLG1_DROME (445-923): 5.3e-145: 456: 21.50		1433E_DROME (1-254): 2.95e-146: 411: 82.69
+	Mm
		910234 MARK2_MOUSE (4-680): 4.24e-139: 435: 18.30		1433E_MOUSE (1-255): 4.87e-154: 430: 100.00
+	Hs
		647862 MARK3_HUMAN (4-669): 7.23e-139: 434: 19.62		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Mm
		910231 MARK3_MOUSE (4-641): 6.86e-139: 434: 19.88		1433E_MOUSE (1-255): 4.87e-154: 430: 100.00
+	Xl
		223345 Q8QGV3_XENLA (4-641): 3.52e-139: 436: 19.82		O57468_XENLA (1-255): 1.7e-152: 426: 96.47
+	Mm
		910308 MARK4_MOUSE (4-628): 8.62e-136: 426: 19.69		1433E_MOUSE (1-255): 4.87e-154: 430: 100.00
+	Hs
		909916 MARK4_HUMAN (4-628): 5.86e-135: 423: 19.53		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Xl
		223344 Q804T2_XENLA (4-641): 3.69e-135: 423: 20.43		O57468_XENLA (1-255): 1.7e-152: 426: 96.47
+	Hs
		909532 KCC2D_HUMAN (8-312): 3.56e-88: 291: 47.71		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		910174 KCC2A_HUMAN (8-312): 6.34e-85: 282: 46.08		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909531 KCC2G_HUMAN (8-312): 4.57e-83: 280: 46.08		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00