HitPredict

Interactor 1: CSKP (O14936)
Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)
Gene: CASK

Interactor 2: KCJ12 (Q14500)
ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Inward rectifier K(+) channel Kir2.2v) (Potassium channel, inwardly rectifying subfamily J member 12)
Gene: KCNJ12

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	15024025, 14960569
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 926 Hs			1 433
+	Rn
		852398 CSKP_RAT (1-926): 0: 945: 97.73		KCJ12_RAT (1-433): 0: 726: 95.84
+	Hs
		159173 CSKP_HUMAN (1-926): 0: 973: 100.00		KCNJ4_HUMAN (31-433): 0: 602: 63.58
+	Hs
		1054729 PALS2_HUMAN (347-926): 1.42e-149: 454: 37.65		KCJ12_HUMAN (1-433): 0: 762: 100.00
+	Hs
		1021490 DLG1_HUMAN (405-923): 2.05e-144: 453: 21.91		KCJ12_HUMAN (1-433): 0: 762: 100.00
+	Hs
		942342 DLG4_HUMAN (402-922): 1.14e-145: 451: 22.56		KCJ12_HUMAN (1-433): 0: 762: 100.00
+	Hs
		80982 DLG1_HUMAN (405-923): 2.05e-144: 453: 21.91		KCJ18_HUMAN (1-433): 0: 757: 98.61
+	Rn
		852400 DLG2_RAT (352-923): 1.29e-144: 452: 21.56		KCJ12_RAT (1-433): 0: 726: 95.84
+	Rn
		852397 DLG1_RAT (434-923): 3.1e-143: 450: 22.61		KCJ12_RAT (1-433): 0: 726: 95.84
+	Rn
		677769 DLG4_RAT (402-922): 3.56e-145: 449: 22.56		KCJ12_RAT (1-433): 0: 726: 95.84
+	Hs
		929764 DLG1_HUMAN (405-923): 2.05e-144: 453: 21.91		KCNJ2_HUMAN (6-433): 0: 686: 70.70
+	Hs
		929762 DLG4_HUMAN (402-922): 1.14e-145: 451: 22.56		KCNJ2_HUMAN (6-433): 0: 686: 70.70
+	Rn
		1144360 DLG2_RAT (352-923): 1.29e-144: 452: 21.56		KCNJ2_RAT (6-433): 0: 682: 70.93
+	Rn
		1144015 DLG1_RAT (434-923): 3.1e-143: 450: 22.61		KCNJ2_RAT (6-433): 0: 682: 70.93
+	Mm
		852403 DLG4_MOUSE (402-922): 5.68e-145: 449: 22.37		KCNJ4_MOUSE (32-433): 0: 616: 63.64
+	Hs
		816147 DLG1_HUMAN (405-923): 2.05e-144: 453: 21.91		KCNJ4_HUMAN (31-433): 0: 602: 63.58
+	Hs
		816146 DLG4_HUMAN (402-922): 1.14e-145: 451: 22.56		KCNJ4_HUMAN (31-433): 0: 602: 63.58
+	Hs
		816159 DLG1_HUMAN (405-923): 2.05e-144: 453: 21.91		KCNJ6_HUMAN (40-381): 0: 527: 52.92
+	Dm
		677699 DLG1_DROME (445-923): 5.3e-145: 456: 21.50		Q8IGY2_DROME (18-364): 4.96e-175: 498: 49.01
+	Mm
		291382 DLG4_MOUSE (402-922): 5.68e-145: 449: 22.37		KCNJ1_MOUSE (39-358): 1.54e-172: 489: 49.85
+	Mm
		1143532 DLG4_MOUSE (402-922): 5.68e-145: 449: 22.37		KCJ10_MOUSE (42-354): 1.53e-159: 456: 44.76