Interactor 1: CSKP (O14936)
Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)
Gene: CASK

Interactor 2: CSKI1 (Q8WXD9)
Caskin-1 (CASK-interacting protein 1)
Gene: CASKIN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.828

The method score is based on:

Property Details
Experiments 22153505, 21763699
Identification Methods transmission electron microscopy, cosedimentation in solution, surface plasmon resonance, molecular sieving, blue native page
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Guanylate_kin~SH3_2, PDZ~SAM_1, PDZ~SH3_2, Ank_2~Pkinase, Ank_4~Pkinase, Pkinase~SAM_1, SH3_2~SH3_2
Common GO terms GO:0005737 - cytoplasm
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 926
Hs

1 1431
+ Rn
+ Mm
+ Hs
+ Hs
+ Rn
+ Mm
+ Mm
+ Mm
+ Mm
+ Mm

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Last updated: 15 Jul 2024