HitPredict

Interactor 1: CSKP (O14936)
Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)
Gene: CASK

Interactor 2: MLX (Q9UH92)
Max-like protein X (Class D basic helix-loop-helix protein 13) (bHLHd13) (Max-like bHLHZip protein) (Protein BigMax) (Transcription factor-like protein 4)
Gene: MLX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 926 Hs			1 298
+	Hs
		159129 CSKP_HUMAN (1-926): 0: 973: 100.00		MYC_HUMAN (31-217): 1.72e-34: 131: 19.15
+	Hs
		159133 CSKP_HUMAN (1-926): 0: 973: 100.00		MYCN_HUMAN (43-214): 2.1e-31: 123: 17.44
+	Hs
		347313 PALS1_HUMAN (361-925): 9.64e-148: 454: 27.84		MYC_HUMAN (31-217): 1.72e-34: 131: 19.15
+	Hs
		347148 MARK2_HUMAN (4-680): 5.16e-140: 438: 18.64		MYC_HUMAN (31-217): 1.72e-34: 131: 19.15
+	Hs
		379539 MARK2_HUMAN (4-680): 5.16e-140: 438: 18.64		MYCN_HUMAN (43-214): 2.1e-31: 123: 17.44
+	Hs
		379041 MARK3_HUMAN (4-669): 7.23e-139: 434: 19.62		MYCN_HUMAN (43-214): 2.1e-31: 123: 17.44
+	Hs
		252905 MARK3_HUMAN (4-669): 7.23e-139: 434: 19.62		MITF_HUMAN (116-236): 9.82e-24: 102: 17.42
+	Hs
		346720 KCC2D_HUMAN (8-312): 3.56e-88: 291: 47.71		MYC_HUMAN (31-217): 1.72e-34: 131: 19.15
+	Hs
		346719 KCC2G_HUMAN (8-312): 4.57e-83: 280: 46.08		MYC_HUMAN (31-217): 1.72e-34: 131: 19.15
+	Hs
		380030 KCC2A_HUMAN (8-312): 6.34e-85: 282: 46.08		MYCN_HUMAN (43-214): 2.1e-31: 123: 17.44