HitPredict

Interactor 1: PLD2 (O14939)
Phospholipase D2 (PLD 2) (hPLD2) (EC 3.1.4.4) (Choline phosphatase 2) (PLD1C) (Phosphatidylcholine-hydrolyzing phospholipase D2)
Gene: PLD2

Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.591

Property	Details
Experiments	17276458, 16407827
Identification Methods	anti tag coimmunoprecipitation, fluorescence microscopy, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 933 Hs			1 217
+	Hs
		159323 PLD2_HUMAN (1-933): 0: 1382: 100.00		SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58
+	Rn
		936843 PLD2_RAT (1-933): 0: 1342: 89.60		SRC_RAT (117-215): 2.55e-11: 64.2: 20.79
+	Hs
		433744 PLD1_HUMAN (468-933): 0: 636: 56.45		LYN_HUMAN (129-215): 1.44e-11: 65: 22.47
+	Hs
		522963 PLD1_HUMAN (468-933): 0: 636: 56.45		SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58