Interactor 1: ML12B (O14950)
Myosin regulatory light chain 12B (MLC-2A) (MLC-2) (Myosin regulatory light chain 2-B, smooth muscle isoform) (Myosin regulatory light chain 20 kDa) (MLC20) (Myosin regulatory light chain MRLC2) (SHUJUN-1)
Gene: MYL12B

Interactor 2: MYH9 (P35579)
Myosin-9 (Cellular myosin heavy chain, type A) (Myosin heavy chain 9) (Myosin heavy chain, non-muscle IIa) (Non-muscle myosin heavy chain A) (NMMHC-A) (Non-muscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA)
Gene: MYH9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.895

The method score is based on:

Property Details
Experiments 33961781, 24981860, 35271311, 37071682
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_7~Myosin_head, EF-hand_7~Myosin_N
Common GO terms GO:0001725 - stress fiber
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005903 - brush border
GO:0008360 - regulation of cell shape
and 3 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 172
Hs

1 1960
+ Ce
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm
+ Hs
+ Dm
+ Hs
+ Ce
+ Ce
+ Hs
+ Ce
+ Ce
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024