HitPredict

Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: K2C6A (P02538)
Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK-6A) (Cytokeratin-6D) (CK-6D) (Keratin-6A) (K6A) (Type-II keratin Kb6) (allergen Hom s 5)
Gene: KRT6A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	25416956, 26871637
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 777 Hs			1 564
+	Hs
		159865 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		K2C3_HUMAN (135-479): 1.83e-179: 521: 80.40
+	Hs
		159824 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		K2C75_HUMAN (3-564): 4.11e-101: 318: 67.79
+	Hs
		159796 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		KRT86_HUMAN (46-544): 9.13e-88: 281: 47.80
+	Hs
		160204 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		KRT82_HUMAN (44-557): 9.75e-80: 261: 47.87
+	Hs
		159963 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		K22O_HUMAN (4-491): 3.07e-71: 242: 63.01