HitPredict

Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: EPHA4 (P54764)
Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)
Gene: EPHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0031901 - early endosome membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 777 Hs			1 986
+	Hs
		160004 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		EPHA7_HUMAN (5-986): 0: 1212: 62.37
+	Hs
		159937 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		EPHA5_HUMAN (2-986): 0: 1201: 63.67
+	Hs
		159898 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		EPHA3_HUMAN (26-986): 0: 1182: 63.01
+	Hs
		159900 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		EPHB2_HUMAN (30-983): 0: 1169: 58.47
+	Hs
		277037 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		EPHA4_HUMAN (1-986): 0: 1293: 100.00
+	Hs
		160216 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		EPHA6_HUMAN (5-986): 0: 1140: 57.75
+	Hs
		159899 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		EPHA8_HUMAN (30-981): 0: 1107: 57.11
+	Hs
		277067 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		EPHA7_HUMAN (5-986): 0: 1212: 62.37
+	Hs
		159897 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		EPHA2_HUMAN (27-986): 0: 1059: 50.36
+	Hs
		277036 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		EPHA5_HUMAN (2-986): 0: 1201: 63.67
+	Hs
		872497 GGA3_HUMAN (6-678): 1.67e-44: 173: 13.14		EPHA5_HUMAN (2-986): 0: 1201: 63.67
+	Hs
		277011 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		EPHA3_HUMAN (26-986): 0: 1182: 63.01
+	Hs
		665436 GGA3_HUMAN (6-678): 1.67e-44: 173: 13.14		EPHA3_HUMAN (26-986): 0: 1182: 63.01
+	Hs
		277152 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		EPHA6_HUMAN (5-986): 0: 1140: 57.75
+	Hs
		277012 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		EPHA8_HUMAN (30-981): 0: 1107: 57.11
+	Hs
		665508 STAM1_HUMAN (4-172): 1.45e-42: 164: 28.40		EPHA8_HUMAN (30-981): 0: 1107: 57.11
+	Hs
		277010 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		EPHA2_HUMAN (27-986): 0: 1059: 50.36
+	Hs
		665303 STAM1_HUMAN (4-172): 1.45e-42: 164: 28.40		EPHA2_HUMAN (27-986): 0: 1059: 50.36
+	Hs
		159843 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		INSR_HUMAN (284-902): 1.29e-145: 470: 25.00
+	Hs
		435783 GGA3_HUMAN (6-678): 1.67e-44: 173: 13.14		IGF1R_HUMAN (394-884): 1.97e-137: 447: 29.47