HitPredict

Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: CLH1 (Q00610)
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)
Gene: CLTC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 0.60 0.688

The method score is based on:

Property Details
Experiments 21411634, 28581508, 11532964, 16716190
Identification Methods affinity chromatography technology, pull down, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005764 - lysosome
GO:0005768 - endosome
GO:0005829 - cytosol
GO:0031623 - receptor internalization
GO:0070062 - extracellular exosome
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 777
Hs

1 1675
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Ce
+ Hs
+ Hs
+ Zm
+ Sc
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024