HitPredict

Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: CAV1 (Q03135)
Caveolin-1
Gene: CAV1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005768 - endosome GO:0010628 - positive regulation of gene expression GO:0031623 - receptor internalization GO:0031901 - early endosome membrane GO:0046426 - negative regulation of receptor signaling pathway via JAK-STAT
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 777 Hs			1 178
+	Hs
		277052 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		974886 TM1L2_HUMAN (5-448): 6.41e-50: 185: 17.17		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		974959 STAM1_HUMAN (4-172): 1.45e-42: 164: 28.40		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		974894 ZFY16_HUMAN (137-497): 7.73e-39: 158: 17.76		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		313531 ZFYV9_HUMAN (155-489): 1.2e-38: 157: 20.63		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		272803 TM1L1_HUMAN (5-474): 3.95e-38: 150: 15.19		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		297828 K0754_HUMAN (201-757): 2.05e-18: 93.2: 11.40		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		975083 ANFY1_HUMAN (156-219): 2.38e-14: 79.3: 50.00		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		272796 TM1L1_HUMAN (5-474): 3.95e-38: 150: 15.19		CAV3_HUMAN (32-178): 1.22e-75: 224: 64.00