Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: SMAD4 (Q13485)
Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4)
Gene: SMAD4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 11094085, 16516194
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0008285 - negative regulation of cell population proliferation
GO:0010628 - positive regulation of gene expression
GO:0046872 - metal ion binding
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 777
Hs

1 552
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024