HitPredict

Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21635887
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 777 Hs			1 665
+	Hs
		159946 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		159799 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		VINEX_HUMAN (67-445): 2.37e-15: 81.7: 19.82
+	Ce
		1089160 Q17796_CAEEL (5-737): 9.07e-93: 307: 33.11		Q9U2T9_CAEEL (142-349): 4.59e-14: 78.1: 18.48
+	Hs
		957984 FGD1_HUMAN (2-400): 2.19e-36: 149: 14.81		SPD2A_HUMAN (1-631): 1.05e-46: 180: 14.72
+	Hs
		81660 FGD1_HUMAN (2-400): 2.19e-36: 149: 14.81		B7Z9C6_HUMAN (1-631): 1.83e-45: 176: 14.72
+	Hs
		272799 TM1L1_HUMAN (5-474): 3.95e-38: 150: 15.19		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Ce
		136444 STAM1_CAEEL (6-165): 3.43e-39: 153: 27.55		Q9U2T9_CAEEL (142-349): 4.59e-14: 78.1: 18.48
+	Hs
		957987 FGD1_HUMAN (2-400): 2.19e-36: 149: 14.81		SH3R1_HUMAN (241-599): 5.37e-12: 71.2: 13.28
+	Hs
		548761 ANFY1_HUMAN (156-219): 2.38e-14: 79.3: 50.00		VAV_HUMAN (84-158): 4.66e-13: 74.7: 28.95