Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: VP37B (Q9H9H4)
Vacuolar protein sorting-associated protein 37B (hVps37B) (ESCRT-I complex subunit VPS37B)
Gene: VPS37B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.667

The method score is based on:

Property Details
Experiments 26871637, 32296183, unassigned1304
Identification Methods two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005768 - endosome
GO:0016236 - macroautophagy
GO:0036258 - multivesicular body assembly
GO:0043328 - protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0070062 - extracellular exosome
and 1 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 777
Hs

1 285
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ At

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Last updated: 15 Jul 2024