HitPredict

Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: UBQL4 (Q9NRR5)
Ubiquilin-4 (Ataxin-1 interacting ubiquitin-like protein) (A1Up) (Ataxin-1 ubiquitin-like-interacting protein A1U) (Connexin43-interacting protein of 75 kDa) (CIP75)
Gene: UBQLN4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	16713569
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	VHS~ubiquitin
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 777 Hs			1 601
+	Hs
		160228 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		UBQL1_HUMAN (11-601): 1.16e-127: 389: 59.16
+	Hs
		160220 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		UBQL2_HUMAN (9-601): 6.99e-118: 365: 51.59
+	Hs
		277139 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		UBQL4_HUMAN (1-601): 6.41e-143: 429: 100.00
+	Hs
		277154 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		UBQL1_HUMAN (11-601): 1.16e-127: 389: 59.16
+	Hs
		277153 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		UBQL2_HUMAN (9-601): 6.99e-118: 365: 51.59
+	Hs
		1173032 TM1L2_HUMAN (5-448): 6.41e-50: 185: 17.17		UBQL2_HUMAN (9-601): 6.99e-118: 365: 51.59
+	Hs
		160088 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		UBQLN_HUMAN (14-459): 2.04e-60: 210: 29.39
+	Hs
		1270627 STAM1_HUMAN (4-172): 1.45e-42: 164: 28.40		UBQL2_HUMAN (9-601): 6.99e-118: 365: 51.59
+	Hs
		272826 TM1L1_HUMAN (5-474): 3.95e-38: 150: 15.19		UBQL2_HUMAN (9-601): 6.99e-118: 365: 51.59
+	Hs
		313512 ZFYV9_HUMAN (155-489): 1.2e-38: 157: 20.63		BAG6_HUMAN (2-547): 7.28e-64: 229: 13.41
+	At
		1092374 Q9SRZ7_ARATH (149-508): 4.25e-39: 158: 19.38		UBQ3_ARATH (9-88): 1.35e-32: 129: 30.86
+	At
		285943 TOL6_ARATH (13-146): 6.12e-40: 158: 37.78		UBQ3_ARATH (9-88): 1.35e-32: 129: 30.86
+	At
		1092009 TOL5_ARATH (8-422): 2.49e-40: 156: 16.20		UBQ3_ARATH (9-88): 1.35e-32: 129: 30.86
+	Hs
		277047 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		RS27A_HUMAN (13-99): 1.11e-12: 68.1: 29.55
+	Hs
		924099 STAM1_HUMAN (4-172): 1.45e-42: 164: 28.40		RS27A_HUMAN (13-99): 1.11e-12: 68.1: 29.55
+	Hs
		924051 ZFY16_HUMAN (137-497): 7.73e-39: 158: 17.76		RS27A_HUMAN (13-99): 1.11e-12: 68.1: 29.55