HitPredict

Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.843

Property	Details
Experiments	32296183, 33277362, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	VHS~ubiquitin
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 777 Hs			1 624
+	Hs
		160228 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		160203 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		UBQL4_HUMAN (22-624): 2.17e-124: 382: 54.55
+	Hs
		277153 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		1173032 TM1L2_HUMAN (5-448): 6.41e-50: 185: 17.17		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		277154 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		1270627 STAM1_HUMAN (4-172): 1.45e-42: 164: 28.40		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		272826 TM1L1_HUMAN (5-474): 3.95e-38: 150: 15.19		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		160088 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		UBQLN_HUMAN (5-445): 3.18e-75: 249: 33.00
+	Hs
		277139 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		UBQL4_HUMAN (22-624): 2.17e-124: 382: 54.55
+	Hs
		313512 ZFYV9_HUMAN (155-489): 1.2e-38: 157: 20.63		BAG6_HUMAN (21-580): 4.44e-53: 198: 15.23
+	Hs
		277047 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Hs
		924099 STAM1_HUMAN (4-172): 1.45e-42: 164: 28.40		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Hs
		924051 ZFY16_HUMAN (137-497): 7.73e-39: 158: 17.76		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27