Interactor 1: AURKA (O14965)
Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (Breast tumor-amplified kinase) (Ipl1- and aurora-related kinase 1) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase Ayk1) (Serine/threonine-protein kinase aurora-A)
Gene: AURKA

Interactor 2: CCND2 (P30279)
G1/S-specific cyclin-D2
Gene: CCND2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 28205554
Identification Methods fluorescent resonance energy transfer
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0019901 - protein kinase binding
and 2 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 403
Hs

1 289
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Sc
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024