HitPredict

Interactor 1: AURKA (O14965)
Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (Breast tumor-amplified kinase) (Ipl1- and aurora-related kinase 1) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase Ayk1) (Serine/threonine-protein kinase aurora-A)
Gene: AURKA

Interactor 2: HNRH2 (P55795)
Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed]
Gene: HNRNPH2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	32989298
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0014069 - postsynaptic density
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 403 Hs			1 449
+	Rn
		1144336 AKT3_RAT (29-401): 9.76e-139: 406: 23.76		PABP1_RAT (1-448): 5.59e-81: 264: 12.29
+	Hs
		160457 AURKA_HUMAN (1-403): 2.51e-162: 463: 100.00		HNRPF_HUMAN (1-434): 2.49e-60: 204: 71.72
+	Hs
		568649 KAPCA_HUMAN (117-400): 5.82e-136: 394: 29.76		PABP4_HUMAN (1-447): 1.01e-81: 266: 13.59
+	Hs
		516351 KAPCA_HUMAN (117-400): 5.82e-136: 394: 29.76		PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29
+	Hs
		1031427 AURKB_HUMAN (126-395): 6.86e-131: 381: 71.43		PABP4_HUMAN (1-447): 1.01e-81: 266: 13.59
+	Mm
		193428 KPCE_MOUSE (4-401): 1.29e-136: 409: 24.57		HNRH1_MOUSE (1-449): 5.42e-73: 238: 95.99
+	Hs
		516639 AURKB_HUMAN (126-395): 6.86e-131: 381: 71.43		PABP1_HUMAN (1-448): 4.82e-81: 264: 12.29
+	Hs
		1292216 AURKB_HUMAN (126-395): 6.86e-131: 381: 71.43		PABP3_HUMAN (1-446): 2.6e-77: 254: 12.23
+	Hs
		1119143 AURKB_HUMAN (126-395): 6.86e-131: 381: 71.43		PAP1L_HUMAN (1-446): 4e-77: 253: 12.42
+	Hs
		878708 AURKB_HUMAN (126-395): 6.86e-131: 381: 71.43		HNRH2_HUMAN (1-449): 1.46e-74: 242: 100.00
+	Hs
		855170 AURKB_HUMAN (126-395): 6.86e-131: 381: 71.43		HNRPF_HUMAN (1-434): 2.49e-60: 204: 71.72
+	Hs
		160652 AURKA_HUMAN (1-403): 2.51e-162: 463: 100.00		RB12B_HUMAN (10-194): 6.44e-19: 91.8: 22.06
+	Hs
		160572 AURKA_HUMAN (1-403): 2.51e-162: 463: 100.00		SART3_HUMAN (2-217): 3.71e-16: 83.3: 23.45
+	Hs
		160374 AURKA_HUMAN (1-403): 2.51e-162: 463: 100.00		NUCL_HUMAN (4-404): 6.61e-09: 60.2: 18.16
+	Hs
		1221290 AURKB_HUMAN (126-395): 6.86e-131: 381: 71.43		RB12B_HUMAN (10-194): 6.44e-19: 91.8: 22.06
+	Hs
		1063265 AURKB_HUMAN (126-395): 6.86e-131: 381: 71.43		SART3_HUMAN (2-217): 3.71e-16: 83.3: 23.45