HitPredict

Interactor 1: AURKA (O14965)
Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (Breast tumor-amplified kinase) (Ipl1- and aurora-related kinase 1) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase Ayk1) (Serine/threonine-protein kinase aurora-A)
Gene: AURKA

Interactor 2: CE128 (Q6ZU80)
Centrosomal protein of 128 kDa (Cep128)
Gene: CEP128

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26638075, 32989298
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005814 - centriole
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 403 Hs			1 1094
+	Hs
		568711 KAPCA_HUMAN (117-400): 5.82e-136: 394: 29.76		CE128_HUMAN (1-1094): 2.14e-74: 269: 100.00
+	Mm
		554901 KPCE_MOUSE (4-401): 1.29e-136: 409: 24.57		MYH6_MOUSE (364-1091): 9.29e-30: 130: 13.19
+	Hs
		528359 KAPCB_HUMAN (117-400): 2.4e-135: 393: 30.80		MYH6_HUMAN (3-795): 2.32e-31: 136: 12.35
+	Hs
		728503 AURKB_HUMAN (126-395): 6.86e-131: 381: 71.43		MYH11_HUMAN (346-1092): 3.9e-34: 144: 12.22
+	Mm
		554927 KPCE_MOUSE (4-401): 1.29e-136: 409: 24.57		MYH7_MOUSE (2-612): 1.29e-22: 107: 12.52
+	Hs
		522653 AURKC_HUMAN (115-389): 7.45e-130: 377: 68.73		MYH7_HUMAN (2-612): 1.16e-22: 107: 12.52
+	Hs
		724784 KPCE_HUMAN (4-401): 3.82e-137: 410: 24.33		MYH9_HUMAN (774-1094): 9.26e-12: 71.7: 9.20
+	Hs
		568568 KAPCA_HUMAN (117-400): 5.82e-136: 394: 29.76		MYH10_HUMAN (662-1091): 3.2e-16: 86.4: 11.32
+	Hs
		551672 KPCE_HUMAN (4-401): 3.82e-137: 410: 24.33		DESP_HUMAN (169-971): 2.18e-10: 67.4: 19.90
+	Hs
		681696 AKT1_HUMAN (27-401): 3.06e-138: 404: 25.07		MYH9_HUMAN (774-1094): 9.26e-12: 71.7: 9.20
+	Hs
		551616 AKT1_HUMAN (27-401): 3.06e-138: 404: 25.07		DESP_HUMAN (169-971): 2.18e-10: 67.4: 19.90
+	Hs
		725220 AURKB_HUMAN (126-395): 6.86e-131: 381: 71.43		MYH10_HUMAN (662-1091): 3.2e-16: 86.4: 11.32
+	Hs
		568567 KAPCA_HUMAN (117-400): 5.82e-136: 394: 29.76		MYH9_HUMAN (774-1094): 9.26e-12: 71.7: 9.20
+	Hs
		149166 AURKB_HUMAN (126-395): 6.86e-131: 381: 71.43		CTRO_HUMAN (8-579): 1.39e-14: 81.1: 11.50
+	Hs
		610795 KAPCB_HUMAN (117-400): 2.4e-135: 393: 30.80		MYH2_HUMAN (781-1093): 1.39e-10: 67.9: 9.75
+	Hs
		610802 KAPCB_HUMAN (117-400): 2.4e-135: 393: 30.80		MYH4_HUMAN (756-1094): 1.08e-09: 65.2: 11.70
+	Hs
		522538 KAPCB_HUMAN (117-400): 2.4e-135: 393: 30.80		MYH1_HUMAN (776-1093): 5.06e-09: 62.9: 8.98
+	Hs
		724962 AURKB_HUMAN (126-395): 6.86e-131: 381: 71.43		MYH9_HUMAN (774-1094): 9.26e-12: 71.7: 9.20
+	Hs
		551805 AURKB_HUMAN (126-395): 6.86e-131: 381: 71.43		DESP_HUMAN (169-971): 2.18e-10: 67.4: 19.90
+	Hs
		522582 AURKC_HUMAN (115-389): 7.45e-130: 377: 68.73		MYH1_HUMAN (776-1093): 5.06e-09: 62.9: 8.98