HitPredict

Interactor 1: AURKA (O14965)
Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (Breast tumor-amplified kinase) (Ipl1- and aurora-related kinase 1) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase Ayk1) (Serine/threonine-protein kinase aurora-A)
Gene: AURKA

Interactor 2: TR150 (Q9Y2W1)
Thyroid hormone receptor-associated protein 3 (BCLAF1 and THRAP3 family member 2) (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150)
Gene: THRAP3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32989298
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 403 Hs			1 955
+	Hs
		969120 KPCE_HUMAN (4-401): 3.82e-137: 410: 24.33		TR150_HUMAN (1-955): 9.81e-127: 408: 100.00
+	Hs
		969115 KPCE_HUMAN (4-401): 3.82e-137: 410: 24.33		BCLF1_HUMAN (38-949): 3.55e-78: 276: 33.19
+	Hs
		1292258 AURKB_HUMAN (126-395): 6.86e-131: 381: 71.43		BCLF1_HUMAN (38-949): 3.55e-78: 276: 33.19
+	Hs
		160565 AURKA_HUMAN (1-403): 2.51e-162: 463: 100.00		MDC1_HUMAN (2-649): 1.14e-11: 71.2: 8.49
+	Hs
		1292304 AURKB_HUMAN (126-395): 6.86e-131: 381: 71.43		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		1186099 AKT3_HUMAN (29-401): 1.27e-140: 411: 23.76		MICA3_HUMAN (169-857): 2.66e-09: 63.4: 7.24
+	Hs
		1056933 AURKB_HUMAN (126-395): 6.86e-131: 381: 71.43		MDC1_HUMAN (2-649): 1.14e-11: 71.2: 8.49